• The association between age at menarche and chronic pain outcomes in women: the Tromsø Study, 2007 to 2016 

      Lund, Charlotte I.; Engdahl, Bo Lars; Rosseland, Leiv Arne; Stubhaug, Audun; Grimnes, Guri; Furberg, Anne-Sofie; Steingrímsdóttir, Ólöf Anna; Nielsen, Christopher Sivert (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-03-01)
      Sex differences in chronic pain are well established with documented predominance in women. This study assessed relationships between age at menarche and chronic pain, site-specific chronic pain, pain characteristics, and chronic widespread pain (CWP). We used data from the Tromsø Study conducted in 2007 to 2008 and 2015 to 2016 (Tromsø 6 and Tromsø 7 waves) including participants aged 30 to 99 ...
    • A bidirectional study of the association between insomnia, high-sensitivity C-reactive protein, and comorbid low back pain and lower limb pain 

      Ho, Kevin Kwan Ngai; Skarpsno, Eivind S.; Nilsen, Kristian Bernhard; Ferreira, Paulo Herrique; Pinheiro, Marina; Hopstock, Laila Arnesdatter; Johnsen, Marianne Bakke; Steingrímsdóttir, Ólöf Anna; Nielsen, Christopher Sivert; Stubhaug, Audun; Simic, Milena (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-04-14)
      Objectives - To examine the possible bidirectional association between insomnia and comorbid chronic low back pain (LBP) and lower limb pain and to explore whether high-sensitivity C-reactive protein (hsCRP) amplifies these associations.<p> <p>Methods - We calculated adjusted risk ratios (RR) with 95% confidence intervals (CI) for the development of insomnia and mild-to-severe chronic LBP and ...
    • Consistent pattern between physical activity measures and chronic pain levels: the Tromsø Study 2015-2016 

      Fjeld, Mats Kirkeby; Årnes, Anders; Engdahl, Bo Lars; Morseth, Bente; Hopstock, Laila Arnesdatter; Horsch, Alexander; Stubhaug, Audun; Strand, Bjørn Heine; Nielsen, Christopher Sivert; Steingrímsdóttir, Ólöf Anna (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-09-08)
      Epidemiological literature on the relationship between physical activity and chronic pain is scarce and inconsistent. Hence, our aim was to assess the relationship applying comprehensive methodology, including self-reported and accelerometer measures of physical activity and different severity levels of chronic pain. We used data from the Tromsø Study (2015-2016). All residents in the municipality, ...
    • The educational gradient in premature cardiovascular mortality: Examining mediation by risk factors in cohorts born in the 1930s, 1940s and 1950s 

      Ariansen, Inger; Strand, Bjørn Heine; Kjøllesdal, Marte Karoline Råberg; Steingrímsdóttir, Ólöf Anna; Mortensen, Laust Hvas; Stigum, Hein; Graff-Iversen, Sidsel; Næss, Øyvind (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-01-28)
      <i>Aims</i>: Educational inequality in cardiovascular disease and in modifiable risk factors changes over time and between birth cohorts. We aimed to assess how cardiovascular disease risk factors mediate educational differences in premature cardiovascular disease mortality and how this varies over birth cohorts and sex.<p> <p><i>Methods</i>: We followed 360,008 40–45-year-olds born in the ...
    • Investigating the Burden of Chronic Pain: An Inflammatory and Metabolic Composite 

      Sibille, Kimberly T; Steingrímsdóttir, Ólöf Anna; Fillingim, Roger B; Stubhaug, Audun; Schirmer, Henrik; Chen, Huaihou (Journal article; Tidsskriftartikkel; Peer reviewed, 2016-02-17)
      BACKGROUND. Chronic pain is associated with increased morbidity and mortality, predominated by cardiovascular disease and cancer. Investigating related risk factor measures may elucidate the biological burden of chronic pain. OBJECTIVES. We hypothesized that chronic pain severity would be positively associated with the risk factor composite. METHODS. Data from 12,982 participants in the 6th Tromsø ...
    • Longitudinal relationships between habitual physical activity and pain tolerance in the general population 

      Årnes, Anders; Nielsen, Christopher Sivert; Stubhaug, Audun; Fjeld, Mats Kirkeby; Johansen, Aslak; Morseth, Bente; Strand, Bjørn Heine; Wilsgaard, Tom; Steingrímsdóttir, Ólöf Anna (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-05-24)
      Physical activity (PA) might influence the risk or progression of chronic pain through pain tolerance. Hence, we aimed to assess whether habitual leisure-time PA level and PA change affects pain tolerance longitudinally in the population. Our sample (n = 10,732; 51% women) was gathered from the sixth (Tromsø6, 2007–08) and seventh (Tromsø7, 2015–16) waves of the prospective population-based Tromsø ...
    • Pain tolerance after stroke: The Tromsø study 

      Melum, Tonje Anita; Årnes, Anders; Stigum, Hein; Stubhaug, Audun; Steingrímsdóttir, Ólöf Anna; Mathiesen, Ellisiv B.; Nielsen, Christopher Sivert (Journal article; Tidsskriftartikkel, 2023-05-11)
      Background: Stroke lesions might alter pain processing and modulation by affecting the widely distributed network of brain regions involved. We aimed to compare pain tolerance in stroke survivors and stroke-free persons in the general population, with and without chronic pain.<p> <p>Methods: We included all participants of the sixth and seventh wave of the population-based Tromsø Study who had ...
    • Physical activity and cold pain tolerance in the general population 

      Årnes, Anders; Nielsen, Christopher Sivert; Stubhaug, Audun; Fjeld, Mats Kirkeby; Hopstock, Laila Arnesdatter; Horsch, Alexander; Johansen, Aslak; Morseth, Bente; Wilsgaard, Tom; Steingrímsdóttir, Ólöf Anna (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-11-09)
      <p>Background - The relationship between habitual physical activity (PA) and experimental pain tolerance has been investigated in small samples of young, healthy and/or single‐sex volunteers. We used a large, population‐based sample to assess this relationship in men and women with and without chronic pain. <p>Methods - We used data from the sixth and seventh Tromsø Study surveys (2007–2008; ...
    • Physical exercise and chronic pain in university students 

      Grasdalsmoen, Michael; Engdahl, Bo Lars; Fjeld, Mats Kirkeby; Steingrímsdóttir, Ólöf Anna; Nielsen, Christopher Sivert; Eriksen, Hege Randi; Lønning, Kari Jussie; Sivertsen, Børge (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-06-26)
      <i>Background</i> - Physical inactivity and chronic pain are both major public health concerns worldwide. Although the health benefits of regular physical exercise are well-documented, few large epidemiological studies have investigated the association between specific domains of physical exercise and chronic pain in young adults. We sought to investigate the association between frequency, intensity ...
    • Tinnitus and associations with chronic pain: The population-based Tromsø Study (2015-2016) 

      Ausland, Jannike Heyerdahl-Larsen; Engdahl, Bo Lars; Oftedal, Bente Margaret; Steingrímsdóttir, Ólöf Anna; Nielsen, Christopher Sivert; Hopstock, Laila Arnesdatter; Johnsen, Magnar; Friborg, Oddgeir; Rosenvinge, Jan H; Eggen, Anne Elise; Krog, Norun Hjertager (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-03-02)
      Tinnitus and pain have many similarities. Both are subjective sensations that may turn chronic, they are often accompanied by hypersensitivity in their respective sensory system, and overlapping brain changes have been observed. Since no population study has examined the empirical association between chronic pain and tinnitus, the present study aimed to explore the relationship in a general adult ...